Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy
نویسندگان
چکیده
منابع مشابه
The TIGIT/CD226 axis regulates human T cell function.
T cell Ig and ITIM domain (TIGIT) is a newly identified receptor expressed on T cells that binds to CD155 on the dendritic cell surface, driving them to a more tolerogenic phenotype. Given that TIGIT contains an ITIM motif in its intracellular domain and considering the potential importance of the TIGIT/CD226 pathway in human autoimmune disease, we investigated the specific role of TIGIT in hum...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2021
ISSN: 1976-670X
DOI: 10.5483/bmbrep.2021.54.1.229